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CRISPR method is still limited to some non-humans living species even if a Chinese team tried experiments on humans embryos, (by the way breaking the Oviedo Convention from 1997). A scientific consensus agrees that CRISPR should not be used to upgrade humans but only to correct genetical diseases. However, whether CRISPR is used to correct genetical diseases or to upgrade humans, it will affect human genetical diversity. However, we need this genetical diversity. First, this diversity can prevent a new disease from killing every human being because we are all different. Then, a genetic illness can turn out to be a genetic adaptation. The adaptation of red blood cells’African which turn to have a smalsickle-shaped to prevent from malaria is a good example that Caplan, Parent, Shen, and Plunkett deal with in their report.